Initial Condition Assessment for Reaction-Diffusion Glioma Growth Models: A Translational MRI-Histology (In)Validation Study
Reaction-diffusion models have been proposed for decades to capture the growth of gliomas.Nevertheless, these models require an initial condition: the tumor cell density distribution Anal Beads over the whole brain at diagnosis time.Several works have proposed to relate this distribution to abnormalities visible on magnetic resonance imaging (MRI).